Article
A Single-Nucleotide Polymorphism Upstream of the HLA-C Locus Is Associated With an Anti-Hepatitis C Virus-Seronegative State in a High-Risk Exposed Cohort.
The Journal of infectious diseases - 5 Nov 2018
Thoens Christine, Heinold Andreas, Lindemann Monika, Horn Peter A, Chang Dae-In, Scherbaum Norbert, Timm Joerg, Heinemann Falko M
Abstract excerpt
In this study, we examined the impact of the rs9264942 single-nucleotide polymorphism, previously shown to be associated with human immunodeficiency virus infection status and HLA-C expression, on the hepatitis C virus status in 359 people who inject drugs (PWID). The linkage of rs9264942 alleles to HLA-C antigens assigned to different expression levels was confirmed. Multivariate analysis revealed the age (P =...
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