Article
Effect of serotonin transporter genotype on self-reported efficacy and activity changes of brain prefrontal area in response to placebo.
Die Pharmazie - 2 Jan 2018
Isawa M, Tashiro R, Naruse C, Yamaguchi Y, Itoh H, Nishimura T, Tomi M, Shimada H, Saito H, Mochizuki M, Nakashima E
Abstract excerpt
Patients benefit from drug therapy not only through pharmacological mechanisms, but also through non-pharmacological action (placebo effect), which may be mediated in part by the prefrontal area of the brain. We consider that the difference between responders and non-responders to placebo might be related to polymorphisms in the serotonin transporter-linked polymorphic region (5-HTTLPR). To study this idea, we...
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