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Article

Genetics and the placebo effect: the placebome.

Trends in molecular medicine - 1 May 2015

Hall Kathryn T, Loscalzo Joseph, Kaptchuk Ted J

Abstract excerpt

Placebos are indispensable controls in randomized clinical trials (RCTs), and placebo responses significantly contribute to routine clinical outcomes. Recent neurophysiological studies reveal neurotransmitter pathways that mediate placebo effects. Evidence that genetic variations in these pathways can modify placebo effects raises the possibility of using genetic screening to identify placebo responders and...

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Identifiers

PMID: 25883069
DOI: 10.1016/j.molmed.2015.02.009
PMCID: PMC4573548

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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