Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

5-HTTLPR polymorphism impacts task-evoked and resting-state activities of the amygdala in Han Chinese.

PloS one - 1 Jan 2012

Li Sufang, Zou Qihong, Li Jun, Li Jin, Wang Deyi, Yan Chaogan, Dong Qi, Zang Yu-Feng

Abstract excerpt

BACKGROUND: Prior research has shown that the amygdala of carriers of the short allele (s) of the serotonin transporter (5-HTT) gene (5-HTTLPR) have a larger response to negative emotional stimuli and higher spontaneous activity during the resting state than non-carriers. However, recent studies have suggested that the effects of 5-HTTLPR may be specific to different ethnic groups. Few studies have been conducted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amygdala
Share to Asian People
Share to Basal Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Behavior

Share to Emotions

Share to Ethnicity

Share to Serotonin Plasma Membrane Transport Proteins

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 22574175
DOI: 10.1371/journal.pone.0036513
PMCID: PMC3344896

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

5-HTTLPR polymorphism impacts task-evoked and resting-state activities of the amygdala in Han Chinese.PMID 22574175Read ↗

The long rather than the short allele of 5-HTTLPR predisposes Han Chinese to anxiety and reduced connectivity between prefrontal cortex and amygdala.Semantic proximity Read ↗

Emotion specific modulation of automatic amygdala responses by 5-HTTLPR genotype.Semantic proximity Read ↗

Genetic variation in the serotonin transporter modulates neural system-wide response to fearful faces.Semantic proximity Read ↗

Serotonin transporter genotype modulates amygdala activity during mood regulation.Semantic proximity Read ↗

Serotonin transporter genetic variation and the response of the human amygdala.Semantic proximity Read ↗

Serotonin transporter genotype modulates the association between depressive symptoms and amygdala activity among psychiatrically healthy adults.Semantic proximity Read ↗

Genetic variation in serotonin transporter alters resting brain function in healthy individuals.Semantic proximity Read ↗

Volition diminishes genetically mediated amygdala hyperreactivity.Semantic proximity Read ↗

The 5-HTTLPR Polymorphism Affects Network-Based Functional Connectivity in the Visual-Limbic System in Healthy Adults.Semantic proximity Read ↗

Beyond affect: a role for genetic variation of the serotonin transporter in neural activation during a cognitive attention task.Semantic proximity Read ↗

Serotonergic genes and amygdala activity in response to negative affective facial stimuli in Korean women.Semantic proximity Read ↗

Serotonin transporter polymorphism modulates N-back task performance and fMRI BOLD signal intensity in healthy women.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.