Article
Controlled clinical comparison of paroxetine and fluvoxamine considering the serotonin transporter promoter polymorphism.
International clinical psychopharmacology - 1 May 2005
Kato Masaki, Ikenaga Yuka, Wakeno Masataka, Okugawa Gaku, Nobuhara Kenji, Fukuda Tsuyoshi, Fukuda Kazuhiro, Azuma Junichi, Kinoshita Toshihiko
Abstract excerpt
The present study aimed to compare the effects of two currently used selective serotonin reuptake inhibitors (SSRIs) in Japan taking the individual background in 5-HTT gene-linked polymorphic region (5HTTLPR) genotype into account. Clinical responses to paroxetine and fluvoxamine were evaluated by total and cluster depressive symptoms for 81 Japanese patients who were diagnosed with major depression. Patients...
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