Article
[Self-rated Caffeine Sensitivity: Implications for Personalized Sleep Medicine?].
Praxis - 11 May 2016
Landolt Hans Peter
Abstract excerpt
The prevalence of the insomnia syndrome and the effects of caffeine on sleep are in part genetically determined. Pharmacogenetic studies in humans demonstrate that functional polymorphisms of the genes encoding adenosine A2A receptors and dopamine transporters contribute to individual differences in impaired sleep quality by caffeine. The A2A receptor and dopamine transporter are preferentially expressed in the...
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