Article
Susceptibility to Hypertensive Renal Disease in the Spontaneously Hypertensive Rat Is Influenced by 2 Loci Affecting Blood Pressure and Immunoglobulin Repertoire.
Hypertension (Dallas, Tex. : 1979) - 1 Apr 2018
Dhande Isha S, Cranford Stacy M, Zhu Yaming, Kneedler Sterling C, Hicks M John, Wenderfer Scott E, Braun Michael C, Doris Peter A
Abstract excerpt
High blood pressure exerts its deleterious effects on health largely through acceleration of end-organ diseases. Among these, progressive loss of renal function is particularly important, not only for the direct consequences of kidney damage but also because loss of renal function is associated with amplification of other adverse cardiovascular outcomes. Genetic susceptibility to hypertension and associated...
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