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Article

Identification of a Good-Prognosis IDH-Mutant-Like Population of Patients with Diffuse Gliomas.

Current molecular medicine - 9 Mar 2018

Wang Z, Liu X, Wang Z, Bao Z, Zhang W, Zhang C, Jiang T

Abstract excerpt

BACKGROUND: Isocitrate dehydrogenase (IDH) mutation is the initiating event that defines major clinical and prognostic classes of gliomas, but the potential mechanisms have not been well interpreted yet. The main objective of the current study was to better understand the underlying biology of IDH mutant gliomas as captured by gene expression profiles. METHODS: RNA sequencing data of WHO grade II-IV gliomas from...

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PMID: 29437008
DOI: 10.2174/1566524018666180212151429

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