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IDH1 Non-Canonical Mutations and Survival in Patients with Glioma

19 Feb 2021

Abstract excerpt

Background: Non-canonical mutations of the isocitrate dehydrogenase (IDH) genes have been described in about 20–25% and 5–12% of patients with WHO grade II and III gliomas, respectively. To date, the prognostic value of these rare mutations is still a topic of debate. Methods: We selected patients with WHO grade II and III gliomas and IDH1 mutations with available tissue samples for next-generation sequencing....

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PMID: 33669525
DOI: 10.3390/diagnostics11020342

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