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Article

Perspectives on IDH Mutation in Diffuse Gliomas.

Trends in cancer - 1 Sept 2018

Su Yu-Ting, Phan Funita P, Wu Jing

Abstract excerpt

Isocitrate dehydrogenase (IDH) mutations are biomarkers to classify diffuse gliomas into biologically similar subgroups. Tremendous efforts have been made to understand the biology of IDH-mutant gliomas at the genetic, epigenetic, transcriptional, and protein levels. Preclinical models that recapitulate human tumor biology are crucial not only to our understanding of IDH mutations in gliomagenesis, but also in...

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Identifiers

PMID: 30149878
DOI: 10.1016/j.trecan.2018.06.006
PMCID: PMC10335607

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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