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Molecular classification of IDH-mutant glioblastomas based on gene expression profiles

13 Feb 2019

Abstract excerpt

Isocitrate dehydrogenase (IDH) mutant glioblastoma (GBM), accounts for ~10% GBMs, arises from lower grade diffuse glioma and preferentially appears in younger patients. Here, we aim to establish a robust gene expression-based molecular classification of IDH-mutant GBM. A total of 33 samples from the Chinese Glioma Genome Atlas RNA-sequencing data were selected as training set, and 21 cases from Chinese Glioma...

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PMID: 30877769
DOI: 10.1093/carcin/bgz032

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