Article
Gene Expression Profiling Stratifies IDH1-Mutant Glioma with Distinct Prognoses.
Molecular neurobiology - 1 Oct 2017
Cheng Wen, Ren Xiufang, Zhang Chuanbao, Cai Jinquan, Han Sheng, Wu Anhua
Abstract excerpt
Isocitrate dehydrogenase (IDH)1 mutation is one of the most important genetic aberrations in glioma. Even several genetic events have refined its prognostic value, the genome-wide expression alteration has not been systematically profiled. In this work, RNA-seq expression data from 310 patients in the Chinese Glioma Genome Atlas database were included as training set, while another 297 patients with microarray...
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