Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heterogeneity in effects of genetically determined adiposity on insulin resistance and type 2 diabetes: The atherosclerosis risk in communities study.

Journal of diabetes and its complications - 1 Mar 2018

Liu Tingting, Li Changwei, Shen Luqi, Shen Ye, Mao Weibo, Li Shengxu

Abstract excerpt

BACKGROUND: A recent genome-wide association study has identified 12 genetic variants robustly associated with body fat percentage (BF%) with diverse cardiometabolic consequences. We developed three genetic risk scores (GRSs) according to the associations of the 12 individual variants with type 2 diabetes (T2D) and test the GRSs' associations with insulin resistance and T2D in the Atherosclerosis Risk in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adiposity
Share to Atherosclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Cohort Studies

Share to Diabetes Mellitus, Type 2

Share to Genome-Wide Association Study

Share to Insulin Resistance

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 29395842
DOI: 10.1016/j.jdiacomp.2017.12.012
PMCID: PMC5820121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heterogeneity in effects of genetically determined adiposity on insulin resistance and type 2 diabetes: The atherosclerosis risk in communities study.PMID 29395842Read ↗

Multiple Metabolic Genetic Risk Scores and Type 2 Diabetes Risk in Three Racial/Ethnic GroupsSemantic proximity Read ↗

Associations Between Type 2 Diabetes-Related Genetic Scores and Metabolic Traits, in Obese and Normal-Weight Youths.Semantic proximity Read ↗

Genetic Risk Phenotypes for Type 2 Diabetes Differ with Ancestry in US Adults with Diabetes and Overweight/Obesity.Semantic proximity Read ↗

Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population.Semantic proximity Read ↗

Development and evaluation of a genetic risk score for obesity.Semantic proximity Read ↗

Heterogeneous effects of genetic variants and traits associated with fasting insulin on cardiometabolic outcomes.Semantic proximity Read ↗

Genetic Evidence for Distinct Biological Mechanisms That Link Adiposity to Type 2 Diabetes: Toward Precision Medicine.Semantic proximity Read ↗

Joint effects of common genetic variants on the risk for type 2 diabetes in U.S. men and women of European ancestry.Semantic proximity Read ↗

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.Semantic proximity Read ↗

Updated genetic score based on 34 confirmed type 2 diabetes Loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program.Semantic proximity Read ↗

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.Semantic proximity Read ↗

Assessment of the potential role of natural selection in type 2 diabetes and related traits across human continental ancestry groups: comparison of phenotypic with genotypic divergence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.