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Article

Genetic Risk Phenotypes for Type 2 Diabetes Differ with Ancestry in US Adults with Diabetes and Overweight/Obesity.

Archives of medical research - 1 Apr 2025

Fowler Lauren A, Fernández José R, O'Neil Patrick M, Parcha Vibhu, Arora Pankaj, Shetty Naman S, Cardel Michelle I, Foster Gary D, Gower Barbara A

Abstract excerpt

BACKGROUND: Type 2 diabetes (T2D) risk is higher among non-Hispanic black (NHB) and Hispanic individuals, for reasons that are unclear. AIMS: With this cross-sectional study, we tested the hypothesis that racial disparities in T2D prevalence can be partially traced to heterogeneity in etiology, as indicated by genetic subtypes that reflect distinct T2D phenotypes. METHODS: Using a diverse sample of 361 US adults...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39579522
DOI: 10.1016/j.arcmed.2024.103128
PMCID: PMC12009211

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