Article
Assessment of the potential role of natural selection in type 2 diabetes and related traits across human continental ancestry groups: comparison of phenotypic with genotypic divergence.
Diabetologia - 1 Dec 2020
Hanson Robert L, Van Hout Cristopher V, Hsueh Wen-Chi, Shuldiner Alan R, Kobes Sayuko, Sinha Madhumita, Baier Leslie J, Knowler William C
Abstract excerpt
AIMS/HYPOTHESIS: Prevalence of type 2 diabetes differs among human ancestry groups, and many hypotheses invoke differential natural selection to account for these differences. We sought to assess the potential role of differential natural selection across major continental ancestry groups for diabetes and related traits, by comparison of genetic and phenotypic differences. METHODS: This was a cross-sectional...
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