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Article

Associations Between Type 2 Diabetes-Related Genetic Scores and Metabolic Traits, in Obese and Normal-Weight Youths.

The Journal of clinical endocrinology and metabolism - 1 Nov 2016

Morandi Anita, Bonnefond Amélie, Lobbens Stéphane, Yengo Loïc, Miraglia Del Giudice Emanuele, Grandone Anna, Lévy-Marchal Claire, Weill Jacques, Maffeis Claudio, Froguel Philippe

Abstract excerpt

CONTEXT: Young-onset obesity is strongly associated with the early development of type 2 diabetes (T2D). Genetic risk scores (GRSs) related to T2D might help predicting the early impairment of glucose homeostasis in obese youths. OBJECTIVE: Our objective was to investigate the contributions of four GRSs (associated with: T2D [GRS-T2D], beta-cell function [GRS-β], insulin resistance [GRS-IR], and body mass index)...

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Identifiers

PMID: 27588439
DOI: 10.1210/jc.2016-2432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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