MMP12 -82 A>G Promoter Polymorphism in Bronchial Asthma in a Population of Central Bulgaria.

doi:10.1093/labmed/lmx085

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Article

MMP12 -82 A>G Promoter Polymorphism in Bronchial Asthma in a Population of Central Bulgaria.

Laboratory medicine - 5 Jul 2018

Tacheva Tanya, Dimov Dimo, Aleksandrova Elina, Bialecka Monika, Gulubova Maya, Vlaykova Tatyana

Abstract excerpt

A characteristic feature of inflamed lungs in bronchial asthma (BA) is airway remodeling. Due to limited information on this topic in the literature, we aimed to explore the possible role of polymorphisms in the promoter region of the macrophage elastase gene MMP12 82A>G (rs2276109) as a predisposing factor for BA in an ethnic Bulgarian population. Using restriction fragment length polymorphism analysis of...

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PMID: 29390099
DOI: 10.1093/labmed/lmx085

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MMP12

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