Article
Association study of matrix metalloproteinase-12 gene polymorphisms and asthma in a Japanese population.
International archives of allergy and immunology - 1 Jan 2013
Yamaide Fumiya, Undarmaa Siizkhuu, Mashimo Yoichi, Shimojo Naoki, Arima Takayasu, Morita Yoshinori, Hirota Tomomitsu, Fujita Kimie, Miyatake Akihiko, Doi Satoru, Sato Kazuki, Suzuki Shuichi, Nishimuta Toshiyuki, Watanabe Hiroko, Hoshioka Akira, Tomiita Minako, Yamaide Akiko, Watanabe Misa, Okamoto Yoshitaka, Kohno Yoichi, Tamari Mayumi, Hata Akira, Suzuki Yoichi
Abstract excerpt
BACKGROUND: Matrix metalloproteinase 12 gene (MMP12) has been shown to be associated with asthma in a Caucasian population. In this study, we investigate whether single-nucleotide polymorphisms (SNPs) of MMP12 are associated with a risk for asthma in a Japanese population. METHODS: We tested for an association between SNPs in MMP12 and asthma, including its severity, in a Japanese population (630 pediatric and...
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