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Article

Matrix metalloproteinases gene variants in idiopathic disseminated bronchiectasis.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Mar 2009

Stankovic Marija, Nikolic Aleksandra, Divac Aleksandra, Rakicevic Ljiljana, Tomovic Andrija, Mitic-Milikic Marija, Nagorni-Obradovic Ljudmila, Grujic Milan, Petrovic-Stanojevic Natasa, Andjelic-Jelic Marina, Dopudja-Pantic Vesna, Radojkovic Dragica

Abstract excerpt

BACKGROUND: The excess of matrix metalloproteinases (MMPs) might be associated with the airways destruction or dilatation in bronchiectasis. The functional promoter polymorphisms of MMP1 and MMP9 genes, involved in the extracellular matrix remodeling, might increase the expression of MMPs leading to the development of bronchiectasis. METHODS: Detection of MMP1 G-1607GG and MMP9 C-1562T gene variants was performed...

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Share to Bronchiectasis
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Matrix Metalloproteinase 1

Share to Matrix Metalloproteinase 9

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 19188843
DOI: 10.2310/JIM.0b013e318198277c

Genes

MMP9
MMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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