Article
Matrix metalloproteinase-1 polymorphism is associated with persistent airway obstruction in asthma in the Taiwanese population.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Feb 2009
Huang Chien-Da, Lin Shu-Min, Chang Po-Jui, Liu Wen-Te, Wang Chun-Hua, Liu Chien-Ying, Lin Horng-Chyuan, Hsieh Ling-Ling, Kuo Han-Pin
Abstract excerpt
BACKGROUND AND OBJECTIVE: Overexpression of matrix metalloproteinase (MMP)-1 has been demonstrated in asthma, and MMP polymorphisms are known to enhance disease susceptibility. We investigated whether MMP-1 polymorphism is associated with persistent airway obstruction in asthma in the Taiwanese population. METHODS: A total of 131 unrelated Taiwanese subjects were enrolled, age-matched, and divided as follows: (1)...
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