Article
The G allele of MMP12 -82 A > G promoter polymorphism as a protective factor for COPD in Bulgarian population.
Archives of physiology and biochemistry - 1 Dec 2017
Tacheva Tanya, Dimov Dimo, Aleksandrova Elina, Bialecka Monika, Gulubova Maya, Vlaykova Tatyana
Abstract excerpt
Chronic inflammation and remodelling of the small airways are features related to chronic obstructive pulmonary disease (COPD). In the current study, we aimed to explore the possible role of MMP12 -82 A > G (rs2276109) promoter polymorphism in the development of COPD in a population from Bulgaria (167 patients with COPD and 119 control individuals). The genotype and allele distributions differed significantly...
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