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Article

Secretory autophagy of lysozyme in Paneth cells.

Autophagy - 1 Jan 2018

Bel Shai, Hooper Lora V

Abstract excerpt

Secretion of antimicrobial proteins is an important host defense mechanism against bacteria, yet how secretory cells maintain function during bacterial invasion has been unclear. We discovered that Paneth cells, specialized secretory cells in the small intestine, react to bacterial invasion by rerouting a critical secreted antibacterial protein through a macroautophagy/autophagy-based secretion system termed...

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Identifiers

PMID: 29388875
DOI: 10.1080/15548627.2018.1430462
PMCID: PMC5959324

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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