Article
Impact of Paneth Cell Autophagy on Inflammatory Bowel Disease.
Frontiers in immunology - 1 Jan 2018
Wang Shu-Ling, Shao Bo-Zong, Zhao Sheng-Bing, Fang Jun, Gu Lun, Miao Chao-Yu, Li Zhao-Shen, Bai Yu
Abstract excerpt
Intestinal mucosal barrier, mainly consisting of the mucus layer and epithelium, functions in absorbing nutrition as well as prevention of the invasion of pathogenic microorganisms. Paneth cell, an important component of mucosal barrier, plays a vital role in maintaining the intestinal homeostasis by producing antimicrobial materials and controlling the host-commensal balance. Current evidence shows that the...
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