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Article

The role of autophagy in Paneth cell differentiation and secretion.

Mucosal immunology - 1 Jan 2010

Stappenbeck T S

Abstract excerpt

Paneth cells are a small intestinal epithelial cell lineage that is considered to have a role in innate immune function. Recent studies on mice with diminished and/or loss of autophagy have suggested that Paneth cells are a primary target in vivo. Interestingly, loss of autophagy affects the secretion of antimicrobial proteins from Paneth cells. Understanding the intersection of the autophagy pathway with the...

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Identifiers

PMID: 19890269
DOI: 10.1038/mi.2009.121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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