Article
Transcriptional Regulatory Mechanisms in Adipose and Muscle Tissue Associated with Composite Glucometabolic Phenotypes.
Obesity (Silver Spring, Md.) - 1 Mar 2018
Langefeld Carl D, Comeau Mary E, Sharma Neeraj K, Bowden Donald W, Freedman Barry I, Das Swapan K
Abstract excerpt
OBJECTIVE: Tissue-specific gene expression is associated with individual metabolic measures. However, these measures may not reflect the true but latent underlying biological phenotype. This study reports gene expression associations with multidimensional glucometabolic characterizations of obesity, glucose homeostasis, and lipid traits. METHODS: Factor analysis was computed by using orthogonal rotation to...
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