Article
Genetic regulation of adipose tissue transcript expression is involved in modulating serum triglyceride and HDL-cholesterol.
Gene - 20 Oct 2017
Sajuthi Satria P, Sharma Neeraj K, Comeau Mary E, Chou Jeff W, Bowden Donald W, Freedman Barry I, Langefeld Carl D, Parks John S, Das Swapan K
Abstract excerpt
Dyslipidemia is a major contributor to the increased cardiovascular disease and mortality associated with obesity and type 2 diabetes. We hypothesized that variation in expression of adipose tissue transcripts is associated with serum lipid concentrations in African Americans (AAs), and common genetic variants regulate expression levels of these transcripts. Fasting serum lipid levels, genome-wide transcript...
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