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Article

Abnormal behaviours relevant to neurodevelopmental disorders in Kirrel3-knockout mice

17 Jan 2018

Abstract excerpt

Abstract In the nervous system, Kirrel3 is involved in neuronal migration, axonal fasciculation, and synapse formation. Recently, genetic links have been reported between mutations in the KIRREL3 gene and increased risk of neurodevelopmental disorders, including autism spectrum disorder (ASD) and intellectual disability. To elucidate the causal relationship between KIRREL3 deficiency and behavioural abnormalities...

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PMID: 29362445
DOI: 10.1038/s41598-018-19844-7

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