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Article

Polygenic risk for Alzheimer's disease influences precuneal volume in two independent general populations.

Neurobiology of aging - 1 Apr 2018

Li Jin, Zhang Xiaolong, Li Ang, Liu Shu, Qin Wen, Yu Chunshui, Liu Yong, Liu Bing, Jiang Tianzi

Abstract excerpt

Alzheimer's disease (AD) is heritable with complex genetic underpinnings. Based on previous results from large-scale genome-wide association studies, recent studies found an association between the polygenic risk score (PGRS) of AD and the structure of some preselected brain regions, but the effects of AD PGRS on all voxels of the brain have not been fully investigated. In the present study, we examined the...

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Identifiers

PMID: 29358118
DOI: 10.1016/j.neurobiolaging.2017.12.022

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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