Article
Partial tandem duplication of KMT2A (MLL) may predict a subset of myelodysplastic syndrome with unique characteristics and poor outcome
19 Jan 2018
Abstract excerpt
Partial tandem duplication (PTD) of the KMT2A (MLL) gene is detected in approximately 5-10% of cases of acute myeloid leukemia (AML)[1][1]–[5][2] and within cases showing normal karyotype, confers a worse prognosis.[2][3],[6][4],[7][5] In these patients, the duplications are variable in size and
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