Article
Intestinal Epithelial Cell-specific Deletion of α-Mannosidase II Ameliorates Experimental Colitis.
Cell structure and function - 16 Mar 2018
Suzuki Koichiro, Yamada Takahiro, Yamazaki Keiko, Hirota Masato, Ishihara Narumi, Sakamoto Mizuki, Takahashi Daisuke, Iijima Hideki, Hase Koji
Abstract excerpt
Inflammatory bowel disease (IBD) is a refractory disease of the gastrointestinal tract that is believed to develop in genetically susceptible individuals. Glycosylation, a type of post-translational modification, is involved in the development of a wide range of diseases, including IBD, by modulating the function of various glycoproteins. To identify novel genes contributing to the development of IBD, we analyzed...
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