Article

Arthritis-Associated Inflammation Remodels Colonic O-Glycosylation

2026-05-22

Abstract excerpt

The gut-joint axis describes how impaired intestinal epithelial function and increased gut permeability allow luminal factors to enter circulation. This can drive inflammation in Rheumatoid Arthritis, a chronic condition affecting the joint with systemic features. What mechanisms contribute to disease persistence are, as yet, incompletely understood. In health, extensively O⍰glycosylated intestinal mucins are cent...

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Literature Corpus work: e16f1c6b-d87a-544c-a51b-89ddb320f523
DOI: 10.64898/2026.05.20.726588

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