Article
Mutational analysis of MED12 exon 2 in uterine leiomyoma and other common tumors.
International journal of cancer - 15 Sept 2012
Je Eun Mi, Kim Mee Ran, Min Ki Ouk, Yoo Nam Jin, Lee Sug Hyung
Abstract excerpt
Recurrent somatic mutations in MED12 exon 2 have recently been reported in uterine leiomyomas. The recurrent nature of the mutations strongly suggests that the mutations may play important roles in the pathogenesis of uterine leiomyomas. The aim of our study was to see whether MED12 exon 2 mutations occur in other human tumors besides uterine leiomyomas. We also attempted to confirm occurrence of the MED12...
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