Article

Whole-exome sequencing study identifies genes associated with Alzheimer’s disease and related dementias

2022-12-26

Abstract excerpt

Alzheimer’s disease (AD) is the most common form of late-onset neurodegenerative disease. Previous genome-wide association studies have identified numerous common genetic variants associated with AD. The contribution of rare variants to AD remains to be uncovered. AD-by-proxy, based on parental AD status, showed superior statistical power boost in recent AD studies. Using the UK Biobank (UKB) 368,865 whole-exome s...

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Literature Corpus work: 91c87123-6f7e-5d4d-9924-46b61249871c
DOI: 10.1101/2022.12.22.22283864

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