Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SERPINA1 gene expression in whole blood links the rs6647 variant G allele to an increased risk of large artery atherosclerotic stroke.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2020

Liu Qingrong, Cui Pan, Zheng Kai, Wang Junjie, Jiang Wei, Liu Guiyou, Hao Junwei, Liu Haijie

Abstract excerpt

The rs6647 variant G allele in SERPINA1 gene was reported to be associated with the risk of large artery atherosclerotic stroke (LAS), however, the mechanism remains unclear. Here, we performed a functional annotation of the rs6647 variant by using the software HaploReg version 4.1 (HaploReg v4.1). Next, the expression quantitative trait loci (eQTLs) analysis of multiple datasets was conducted for determining the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alleles
Share to alpha 1-Antitrypsin
Share to Atherosclerosis
Share to Case-Control Studies
Share to Gene Expression
Share to Gene Expression Profiling
Share to Quantitative Trait Loci
Share to Stroke

Source

Identifiers

PMID: 32725952
DOI: 10.1096/fj.201903197R

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SERPINA1 gene expression in whole blood links the rs6647 variant G allele to an increased risk of large artery atherosclerotic stroke.PMID 32725952Read ↗

LncRNA SERPINB9P1 expression and polymorphisms are associated with ischemic stroke in a Chinese Han population.Semantic proximity Read ↗

mRNA Expression of GWAS-identified Genes in Peripheral Blood Leukocytes as Identification Biomarkers for Haemorrhagic StrokeSemantic proximity Read ↗

Association of SUMOylation Pathway Genes With Stroke in a Genome-Wide Association Study in India.Semantic proximity Read ↗

Genome-wide association analysis to search for new loci associated with stroke risk in Northwestern Chinese population.Semantic proximity Read ↗

Alzheimer's Disease rs11767557 Variant Regulates EPHA1 Gene Expression Specifically in Human Whole Blood.Semantic proximity Read ↗

Association of GWAS-Supported Variants rs2200733 and rs6843082 on Chromosome 4q25 with Ischemic Stroke in the Southern Chinese Han Population.Semantic proximity Read ↗

Genome-Wide Detection of m6A-Associated Genetic Polymorphisms Associated with Ischemic Stroke.Semantic proximity Read ↗

Association of GWAS-Supported Variants rs556621 on Chromosome 6p21.1 with Large Artery Atherosclerotic Stroke in a Southern Chinese Han Population.Semantic proximity Read ↗

ALOX5AP rs10507391 polymorphism and the risk of ischemic stroke in Caucasians: an update meta-analysis.Semantic proximity Read ↗

Apolipoprotein E polymorphisms are associated with ischemic stroke susceptibility in a Northwest China Han population.Semantic proximity Read ↗

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke.Semantic proximity Read ↗

A promoter polymorphism (rs17222919, -1316T/G) of ALOX5AP gene is associated with decreased risk of ischemic stroke in two independent Chinese populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.