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Article

High-Risk TP53 Mutations Are Associated with Extranodal Extension in Oral Cavity Squamous Cell Carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2018

Sandulache Vlad C, Michikawa Chieko, Kataria Pranav, Gleber-Netto Frederico O, Bell Diana, Trivedi Sanchit, Rao Xiayu, Wang Jing, Zhao Mei, Jasser Samar, Myers Jeffrey N, Pickering Curtis R

Abstract excerpt

Purpose: Development of extranodal extension (ENE) has been associated with poor survival in patients with oral cavity squamous cell carcinoma (OSCC). Here, we sought to confirm the role of ENE as a poor prognostic factor, and identify genomic and epigenetic markers of ENE in order to develop a predictive model and improve treatment selection.Experimental Design: An institutional cohort (The University of Texas...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29330202
DOI: 10.1158/1078-0432.CCR-17-0721
PMCID: PMC5884733

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