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The 'Triple Threat': Extracapsular Extension, Perineural Invasion, and Lymphovascular Invasion as Predictors of Adjuvant Chemoradiation Failure in Head and Neck Squamous Cell Carcinoma

2026-02-18

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<title>Abstract</title> <p> <bold>Background:</bold> The current standard of care for high-risk Head and Neck Squamous Cell Carcinoma (HNSCC) involves surgical resection followed by adjuvant concurrent chemoradiation (CCRT). Despite this aggressive multimodal approach, a subset of patients experiences early locoregional recurrence and distant metastasis. This study aims to define the "Triple Threat" phenotype—t...

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Literature Corpus work
544f0b1a-6df4-5546-9a3b-33fa9f030c72
DOI
10.21203/rs.3.rs-8898146/v1
Open publication

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The 'Triple Threat': Extracapsular Extension, Perineural Invasion, and Lymphovascular Invasion as Predictors of Adjuvant Chemoradiation Failure in Head and Neck Squamous Cell CarcinomaDOI 10.21203/rs.3.rs-8898146/v1
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