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Article

Association of mutations with morphological dysplasia in de novo acute myeloid leukemia without 2016 WHO Classification-defined cytogenetic abnormalities.

Haematologica - 1 Apr 2018

Weinberg Olga K, Gibson Christopher J, Blonquist Traci M, Neuberg Donna, Pozdnyakova Olga, Kuo Frank, Ebert Benjamin L, Hasserjian Robert P

Abstract excerpt

Despite improvements in our understanding of the molecular basis of acute myeloid leukemia (AML), the association between genetic mutations with morphological dysplasia remains unclear. In this study, we evaluated and scored dysplasia in bone marrow (BM) specimens from 168 patients with de novo AML; none of these patients had cytogenetic abnormalities according to the 2016 World Health Organization...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29326119
DOI: 10.3324/haematol.2017.181842
PMCID: PMC5865424

Genes

EFS
NPM1
STAG2
FLT3
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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