Article
Morphologic and Molecular Characteristics of De Novo AML With JAK2 V617F Mutation.
Journal of the National Comprehensive Cancer Network : JNCCN - 1 Jun 2017
Hidalgo-López Juliana E, Kanagal-Shamanna Rashmi, Medeiros L Jeffrey, Estrov Zeev, Yin C Cameron, Verstovsek Srdan, Konoplev Sergej, Jorgensen Jeffrey L, Mohammad Mohammad M, Miranda Roberto N, Zhao Chong, Lee John, Zuo Zhuang, Bueso-Ramos Carlos E
Abstract excerpt
Background:JAK2 V617F mutation (mut) in acute myeloid leukemia (AML) is rare. We describe the clinicopathologic findings of a single-institution series of 11 de novo AML cases with JAK2 V617. Methods: We identified cases of de novo AML with JAK2 V617F over a 10-year period. We reviewed diagnostic peripheral blood and bone marrow (BM) morphologic, cytogenetic, and molecular studies, including next-generation...
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