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Acute myeloid leukemia with myelodysplasia-related changes diagnosed with multilineage dysplasia alone demonstrates a superior clinical outcome.

Human pathology - 1 Oct 2020

Jiang Gina, Capo-Chichi Jose-Mario, Liu Aijun, Atenafu Eshetu G, Guo Robert, Tierens Ann, Minden Mark D, Chang Hong

Abstract excerpt

Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) generally confers poor prognosis; however, the clinical outcome remains heterogeneous. We sought to further stratify this subentity of AML by performing a retrospective analysis of 179 adult patients with AML-MRC diagnosed at our institution. Based on 2016 World Health Organization diagnostic criteria, 44 (25%) patients had multilineage...

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Identifiers

PMID: 32798550
DOI: 10.1016/j.humpath.2020.08.003

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