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AML, NOS and AML-MRC as defined by multilineage dysplasia share a common mutation pattern which is distinct from AML-MRC as defined by MDS-related cytogenetics

20 Jun 2022

Abstract excerpt

Acute myeloid leukemia (AML) is a genetically complex disease. Many different driver mutations are known to cause development of AML, moreover genetic and genomic features are the most important prognostic factors for overall survival [ 1 ]. In addition to cytogenetics, which have been pivotal in AML diagnostics and classification for many years, molecular genetics are becoming more important in everyday...

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PMID: 35725772
DOI: 10.1038/s41375-022-01631-z

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