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Article

Association between genetic polymorphism and levothyroxine bioavailability in hypothyroid patients.

Endocrine journal - 28 Mar 2018

Arici Merve, Oztas Ezgi, Yanar Fatih, Aksakal Nihat, Ozcinar Beyza, Ozhan Gul

Abstract excerpt

Thyroid hormones play a vital role in the human body for growth and differentiation, regulation of energy metabolism, and physiological function. Hypothyroidism is a common endocrine disorder, which generally results from diminished normal circulating concentrations of serum thyroxine (fT4) and triiodothyronine (fT3). The primary choice in hypothyroidism treatment is oral administration of levothyroxine (L-T4), a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29321381
DOI: 10.1507/endocrj.EJ17-0162

Genes

DIO2
DIO1
TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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