Article
Genetic abnormalities in thyroid hormone deiodinases.
Current opinion in endocrinology, diabetes, and obesity - 1 Oct 2015
Taylor Peter N, Peeters Robin, Dayan Colin M
Abstract excerpt
PURPOSE OF REVIEW: The purpose of this study was to review several of the most recent and most important clinical studies regarding the effects of how genetic variation in the deiodinases can influence health. RECENT FINDINGS: Common variation in DIO1 but not DIO2 or DIO3 is robustly associated with thyroid hormone levels at genome-wide levels of significance although the effect is modest. There is growing...
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