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Nonstructural Protein σ1s Is Required for Optimal Reovirus Protein Expression

9 Jan 2018

Abstract excerpt

ABSTRACT Reovirus nonstructural protein σ1s is required for the establishment of viremia and hematogenous viral dissemination. However, the function of σ1s during the reovirus replication cycle is not known. In this study, we found that σ1s was required for efficient reovirus replication in simian virus 40 (SV40)-immortalized endothelial cells (SVECs), mouse embryonic fibroblasts, human umbilical vein endothelial...

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PMID: 29321319
DOI: 10.1128/jvi.02259-17

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