Reovirus growth in cell culture does not require the full complement of viral proteins: identification of a sigma1s-null mutant.

doi:10.1128/JVI.72.11.8597-8604.1998

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Article

Reovirus growth in cell culture does not require the full complement of viral proteins: identification of a sigma1s-null mutant.

Journal of virology - 1 Nov 1998

Rodgers S E, Connolly J L, Chappell J D, Dermody T S

Abstract excerpt

The reovirus sigma1s protein is a 14-kDa nonstructural protein encoded by the S1 gene segment. The S1 gene has been linked to many properties of reovirus, including virulence and induction of apoptosis. Although the function of sigma1s is not known, the sigma1s open reading frame is conserved in...

Topics

Amino Acid Sequence
Animals
Antibodies, Monoclonal
Antibodies, Viral
Apoptosis
Base Sequence
Capsid Proteins
Cell Line
Dogs
Gene Expression Regulation, Developmental
Gene Expression Regulation, Viral
Genes, Viral
Genetic Variation
L Cells
Mammalian orthoreovirus 3
Mice
Mutation
RNA, Viral

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Identifiers

PMID: 9765398
DOI: 10.1128/JVI.72.11.8597-8604.1998
PMCID: PMC110270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9765398-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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