Article
Reovirus mu2 protein determines strain-specific differences in the rate of viral inclusion formation in L929 cells.
Virology - 20 Jun 2000
Mbisa J L, Becker M M, Zou S, Dermody T S, Brown E G
Abstract excerpt
Reovirus infection induces the formation of large cytoplasmic inclusions that serve as the major site of viral assembly. Reovirus strains type 3 Dearing (T3D) and type 1 Lang (T1L) differ in the rate of inclusion formation in L929 cells. The median time of inclusion formation is 18 h in cells infected with T3D and 39 h in cells infected with T1L. Using reassortant viruses that contain combinations of gene...
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