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Article

Comprehensive Evaluation of the Genetic Basis of Keratoconus: New Perspectives for Clinical Translation.

Investigative ophthalmology & visual science - 1 Oct 2024

Cerván-Martín Miriam, Higueras-Serrano Inmaculada, González-Muñoz Sara, Guzmán-Jiménez Andrea, Chaves-Urbano Blas, Palomino-Morales Rogelio J, Poo-López Arancha, Fernández-Vega-Cueto Luis, Merayo-Lloves Jesús, Alcalde Ignacio, Bossini-Castillo Lara, Carmona F David

Abstract excerpt

Purpose: Keratoconus (KC) is a corneal disorder with complex etiology, apparently involving both genetic and environmental factors, characterized by progressive thinning and protrusion of the cornea. We aimed to identify novel genetic regions associated with KC susceptibility, elucidate relevant genes for disease development, and explore the translational implications for therapeutic intervention and risk...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39436372
DOI: 10.1167/iovs.65.12.32
PMCID: PMC11500050

Genes

MINK1

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