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Article

Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos.

Human molecular genetics - 15 Nov 2016

Gao Xiaoyi, Nannini Drew R, Corrao Kristen, Torres Mina, Chen Yii-Der I, Fan Bao J, Wiggs Janey L, Taylor Kent D, Gauderman W James, Rotter Jerome I, Varma Rohit

Abstract excerpt

The cornea is the outermost layer of the eye and is a vital component of focusing incoming light on the retina. Central corneal thickness (CCT) is now recognized to have a significant role in ocular health and is a risk factor for various ocular diseases, such as keratoconus and primary open angle glaucoma. Most previous genetic studies utilized European and Asian subjects to identify genetic loci associated with...

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Source

Open in PubMed Open full text

Identifiers

PMID: 28171582
DOI: 10.1093/hmg/ddw319
PMCID: PMC6078592

Genes

FOXO1
IBTK
RXRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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