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Article

Identification of four novel variants that influence central corneal thickness in multi-ethnic Asian populations.

Human molecular genetics - 15 Jan 2012

Cornes Belinda K, Khor Chiea Chuen, Nongpiur Monisha E, Xu Liang, Tay Wan-Ting, Zheng Yingfeng, Lavanya Raghavan, Li Yang, Wu Renyi, Sim Xueling, Wang Ya-Xing, Chen Peng, Teo Yik Ying, Chia Kee-Seng, Seielstad Mark, Liu Jianjun, Hibberd Martin L, Cheng Ching-Yu, Saw Seang-Mei, Tai E-Shyong, Jonas Jost B, Vithana Eranga N, Wong Tien Y, Aung Tin

Abstract excerpt

Central corneal thickness (CCT) is a highly heritable trait. Genes that significantly influence CCT can be candidate genes for common disorders in which CCT has been implicated, such as primary open-angle glaucoma (POAG) and keratoconus. Because the genetic factors controlling CCT in different As...

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Source

Identifiers

PMID: 21984434
DOI: 10.1093/hmg/ddr463

Genes

AKAP13
CHSY1
IBTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21984434-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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