Article
Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study.
Investigative ophthalmology & visual science - 3 Aug 2020
Chai Xiaoran, Low Kok Yao, Tham Yih Chung, Chee Miao Li, Thakur Sahil, Zhang Liang, Tan Nicholas Y, Khor Chiea Chuen, Aung Tin, Wong Tien Yin, Cheng Ching-Yu
Abstract excerpt
Purpose: Genome-wide association studies have identified several genes associated with glaucoma. However, their roles in the pathogenesis of glaucoma remain unclear, particularly their effects on retinal nerve fiber layer (RNFL) thickness. The aim of this study was to investigate the associations between the identified glaucoma risk genes and RNFL thickness. Methods: A total of 3843 participants (7,020 healthy...
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