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Article

Elevated aggressive behavior in male mice with thyroid-specific Prkar1a and global Epac1 gene deletion.

Hormones and behavior - 1 Feb 2018

Russart Kathryn L G, Huk Danielle, Nelson Randy J, Kirschner Lawrence S

Abstract excerpt

Alterations in circulating thyroid hormone concentrations are associated with several psychological and behavioral disorders. In humans, behavioral disorders such as anxiety, depression, and attention-deficit hyperactivity disorder can be associated with thyroid disease. The Tpo-Cre;Prkar1aflox/flox;Epac1-/- (R1A-Epac1KO) mice, originally bred to investigate the role of exchange protein directly activated by cAMP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclic AMP-Dependent Protein Kinase RIalpha Subunit

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Source

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Identifiers

PMID: 29289659
DOI: 10.1016/j.yhbeh.2017.12.012
PMCID: PMC5828986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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